Translation information

Translated from the Chinese original using automated translation, with terminology checks. This version has not been clinically reviewed in English. For medication decisions, consult your clinician and the Taiwan-approved prescribing information. If wording is unclear, refer to the Chinese original and contact the clinic. Services are provided in Taiwan; this page does not imply English-speaking clinical services are available.

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New direction during maintenance period

Can an oral medicine help maintain weight loss after injections?

Can I take medicine to maintain my condition in the future? New research provides a direction, but it doesn't yet apply directly to everyone.

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Important reminder

When you are close to your target weight, you can start discussing the maintenance plan; whether to change medications needs to be decided together with your doctor.

How do studies compare?

ATTAIN-MAINTAIN found 376 people who had received injections for weight loss and were randomly divided into two groups: one group took orforglipron every day, and the other group took a placebo without active pharmaceutical ingredients to see whether the subsequent weight could be maintained.

The oral medication group was better at maintaining weight

The oral medication group was better at maintaining weight loss than the placebo group. This provides a research direction for maintenance treatment, but it cannot be directly used as a personal dressing change plan.

This does not mean that oral administration is necessarily better than continued injection.

This study followed for one year, had a limited number of people, and was also supported by pharmaceutical companies. It compared oral medication to a placebo and did not directly prove that oral medication was superior to continued injections. Nor can the results be applied to other oral medications or to all people who want to stop taking injections.

When returning to the clinic, you can first discuss your actual needs

For example, if you want to reduce injections, are worried about the cost, or have side effects, you can raise your concerns. As for whether the drug under study is approved in Taiwan, whether it is available, and whether it is suitable for you, it needs to be confirmed separately. You cannot change the drug on your own just after reading the study.

Next time you come back for a consultation, you can ask this question

I'm almost reaching my goal, what are the next steps to maintain it?

Original document

This article summarizes research results and care reminders and cannot replace individual diagnosis and treatment. The drugs or uses under study may not have been approved in Taiwan. Please do not change the medication or adjust the dosage accordingly.

Further reading

How we prepare and update these guides

The content of this website is provided by BH Clinic, referring to original research, drug instructions and professional guidelines, and using AI to assist in organizing. The article will explain the research subjects and limitations and cannot replace medical consultation.

Articles that do not indicate a reviewer and date have not been confirmed to have been reviewed by a physician. If you have any questions, please send the article link and relevant paragraphs to the official LINE for easy verification.

The research publication date, data query date and article update date are marked respectively. For actual medication use, please follow Taiwan’s instructions and instructions from your doctor.

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